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KMID : 0861120000040010087
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Korean Journal of Oriental Preventive Medicine
2000 Volume.4 No. 1 p.87 ~ p.90
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Effects of the Methanol Extract of Houttuynia cordata on the Accumulation of Cadmium in Rats (III)
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Lee Jeong-Ho
You Il-Soo
Lee E.-K.
Chong M.S.
Han J.M.
Jeung J.Y.
Lee Ki-Nam
Baek Seung-Hwa
Kim Shin-Kee
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Abstract
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This study was conducted to investigate the antitoxic component in methanol extract of Houttuynia cordata . The results were as follows: Generally, detoxication effects by Houttuynia cordata methanol extract increased in proportion to the methanol extract concentrations. When 40 mg/kg dosage of Houttuynia cordata methanol extract was administrated, it showed the highest antitoxic effects in metallothionein induction. After the methanol extract treatment. Body weights increased in proportion to methanol extract concentrations. However, after 3 weeks, the body weight decreased insignificantly. From the above results, these results suggest that the methanol extract of Houttuynia cordata increased metallothionein concentration and decreased the toxicity of cadmium in rats.
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KEYWORD
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Houttuynia cordata THUNB, Antitoxic agent, Repaired effect
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